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EC number: 635-156-4 | CAS number: 109293-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
To evaluate the aquatic toxicity of the test substance several studies on fish, aquatic invertebrates and algae and cyanobacteria were performed. The following results are based on the worst case endpoint of each taxonomic group.
Short-term toxicity to fish
The short term toxicity of the test substance to fish was tested in freshwater and in marine water studies. In a 96 -hour static acute toxicity freshwater study with the test substance (free acid of Diflufenzopyr sodium salt) with rainbow trout (Oncorhynchus mykiss) the LC50 value was 106 mg a.i./L. The 96 -hour no observed effect concentration, determined by a visual examination of the mortality data, was 80 mg a.i./L
In a marine water key static study, the 96-hour LC50 value for sheepshead minnows exposed to the test substance (free acid of Diflufenzopyr sodium salt) was > 138 mg a.i./L, the highest concentration tested. The 96-hour no mortality concentration and NOEC were 138 mg a.i./L.
Long term toxicity to fish
In a 21-d long term toxicity study to fathead minnows (Pimephalespromelas) under static-renewal conditions with the test substance (Diflufenzopyr sodium salt), the LOEC for the study, based on dry weight, was 10 mg a.i./L. and the NOEC was 5.0 mg a.i./L.
Short-term toxicity to aquatic invertebrates
The acute toxicity of the test substance (free acid of Diflufenzopyr sodium salt) was tested in a 48 -hour short term toxicity study to aquatic invertebrates. The 48h-EC50 value for the Daphnia magna exposed was >130 a.i. mg/L.
Long-term toxicity to aquatic invertebrates
In a 21 -d long term toxicity study to aquatic invertebrates of the test substance, the daphnia magna exposed to 15 mg a.i./L had statistically reduced survival. In this study, the most sensitive endpoints were reproduction and growth. The NOEC for reproduction was considered to be 1.9 mg a.i./L. The LOEC for reproduction is 3.8 mg a.i./L. The LOEC and the NOEC for growth were determined to be 3.8 mg a.i./L and 1.9 mg a.i./L, respectively.
Toxicity to algae and cyanobacteria
The toxicity of the test substance to algae and cyanobacteria was tested in a freshwater and in marine algae. In a key study of freshwater diatom, the 5-day EC50 was calculated to be 0.10 mg A.E.(acid equivalent)/L (95% confidence limits of 0.033 and 0.36 mg A.E.(acid equivalent)/L.
The 5-day No-Observed-Effect Concentration (NOEC) was determined to be 0.0030 mg A.E.(acid equivalentt)/L.In a key study of marine water diatom, the effects of the test substance observed on the growth of Skeletonema costatum were clearly concentration related and yielded a 5-day EC50 value, based on cell density, of 0.14 mg A.E. (acid equivalent)/L. The 5-day No-Observed-Effect Concentration (NOEC) was determined to be 0.0064 mg A.E.(acid equivalent)/L
Toxicity to aquatic plants other than algae
Based on mean measured concentrations of the test substance (diflufenzopyr sodium salt), the 14-day EC50 for frond density was estimated to be >0.35 mg A.E.(acid equivalent)/L. The 14 -day No-Observed-Effect Concentration (NOEC) for frond density was determined to be 0.0039 mg A.E.(acid equivalent)/L. Based on mean measured concentrations, the 14-day EC50 based on frond biomass was estimated to be >0.35 mg A.E. (acid equivalent)/L, the highest concentration tested. The No-Observed-Effect Concentration (NOEC) for frond biomass was determined to be 0.35 mg A.E.(acid equivalent)/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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