Registration Dossier
Registration Dossier
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EC number: 200-889-7 | CAS number: 75-65-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The potential for tertiary butyl alcohol to cause dermal sensitization is well understood. In a Guinea Pig Maximization Test conducted according to OECD Guidelines, a concentration of 100% tertiary butyl alcohol at challenge did not cause a sensitization reaction in female guinea pigs after prior intradermal exposures of 1% and topical exposures of 100%.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
No information available.
Justification for classification or non-classification
No evidence of a sensitization response was observed in a guideline dermal sensitization study conducted in guinea pigs and the subject chemical is not structurally similar to substances known to cause dermal sensitization. Based on a weight-of-the evidence assessment, tertiary butyl alcohol is not classified for dermal sensitization according to Dangerous Substances Directive 67/548/EEC and EU Classification, Labeling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
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