Registration Dossier
Registration Dossier
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EC number: 202-808-0 | CAS number: 99-99-0
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Principles of method if other than guideline:
- Method: other: see below
- GLP compliance:
- not specified
- Vehicle:
- yes
- Remarks:
- Name and concentration of vehicle : HCO-20, 1st Concentration area : 0.4 ppm, 2nd Concentration area : 0.04 ppm
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- Carp, average weight ca. 24 g
Average length approx. 10 cm - Total exposure / uptake duration:
- 42 d
- Test temperature:
- 25 ± 2 °C
- Nominal and measured concentrations:
- 0.1 ppm and 0.01 ppm
- Conc. / dose:
- 0.01 other: ppm
- Type:
- BCF
- Value:
- 4.5 - 8
- Conc. / dose:
- 0.1 other: ppm
- Type:
- BCF
- Value:
- 3.7 - 7.2
- Validity criteria fulfilled:
- not specified
- Executive summary:
MITI, 1992
In an experimental study similar to OECD guideline 305C, the BCF value in Cyprinus carpio after exposure to 4-nitrotoluene over a period of 6 weeks was determined at two dose levels:
dose level : 0.1 ppm ; BCF values: 3.7 - 7.2
dose level : 0.01 ppm ; BCF values: 4.5 - 8.0
Reference
Description of key information
For transported isolated intermediates according to REACh, Article 18, this endpoint is not a data requirement. However, data is available for this endpoint and is thus reported under the guidance of "all available data".
MITI, 1992
In an experimental study similar to OECD guideline 305C, the BCF value in Cyprinus carpio after exposure to 4-nitrotoluene over a period of 6 weeks was determined at two dose levels:
dose level : 0.1 ppm ; BCF values: 3.7 - 7.2
dose level : 0.01 ppm ; BCF values: 4.5 - 8.0
Key value for chemical safety assessment
- BCF (aquatic species):
- 8 dimensionless
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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