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Diss Factsheets
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EC number: 205-745-7 | CAS number: 149-73-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
1.vPvB ASSESSMENT
1.1 Summary and overall conclusions onPBTor vPvB properties
TMOF is not a PBT or a vPvB substance.
1.2PBT/vPvB criteria and justification
Persistence Assessment
A substance fulfils the persistence criterion (P-) when:
– the half-life in marine water is higher than 60 days, or
– the half-life in fresh- or estuarine water is higher than 40 days, or
– the half-life in marine sediment is higher than 180 days, or
– the half-life in fresh- or estuarine water sediment is higher than 120 days, or
– the half-life in soil is higher than 120 days.
From biodegradability studies TMOF is readily biodegradable. The estimated half life normalised to 10 g fish is 0.05824 days (see BCFBAF v3.01 in Episuite 4.11).
A Mackay levelfugacity model gives the following half lives:
Air 42.79 hours
Water 360 hours (15 days)
Soil 720 hours (30 days)
Sediment 3240 hours (135 days)
Therefore there is no indication that TMOF would be persistent.
Bioaccumulation Assessment
A substance fulfils the bioaccumulation criterion (B-) when:
– the bioconcentration factor () is higher than 2 000.
With an experimental Log K (octanol/water) of 0.09 (< 4.5) and a Log BCF of 0.500 (BCF = 3.162 L/kg wet-wt), calculated (see BCFBAF v3.01 in Episuite 4.11), TMOF is not predicted to be bioaccumulative.
Toxicity Assessment
A substance fulfils the toxicity criterion (T-) when:
– the long-term no-observed effect concentration (NOEC) for marine or freshwater organisms is less than 0.01 mg/l, or
– the substance is classified as carcinogenic (category 1 or 2), mutagenic (category 1or 2), or toxic for reproduction (category 1, 2, or 3), or
– there is other evidence of chronic toxicity, as identified by the classifications: T, R48, or Xn, R48 according to Directive 67/548/.
With a lowest marine/freshwater organism NOEC (daphnia) of 157.194 mg/l, not being CMR and not being T;R48 and/or Xn;R48, TMOF fulfils none of these criteria.
2. Emission Characterisation
From the various estimates in Episuite 4.11 (see Episuite data set) there is no reason to assume that this substance will have an influence on global warming, ozone depletion in the stratosphere, ozone formation in the troposphere, acidification, etc.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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