Registration Dossier
Registration Dossier
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EC number: 203-810-4 | CAS number: 110-87-2
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 3,4-dihydro-2H-pyran
- EC Number:
- 203-810-4
- EC Name:
- 3,4-dihydro-2H-pyran
- Cas Number:
- 110-87-2
- Molecular formula:
- C5H8O
- IUPAC Name:
- 3,4-dihydro-2H-pyran
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 3,4-Dihydro-2H-pyrane
- Analytical purity: 99.3 %
- Lot/batch No.: 61460397G0
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.6
- Temp.:
- 23 °C
- pH:
- 6.5
Any other information on results incl. tables
Individual Results
Component |
tr[min] (mean value out of two determinations) |
ks |
log ks |
log Pow |
Formamide |
1.6 |
|
|
|
2-Butanone |
3.5 |
1.19 |
0.075 |
0.3 |
Acetanilide |
5.2 |
2.2.5 |
0.352 |
1.0 |
Benzonitrile |
9.4 |
4.88 |
0.688 |
1.6 |
4-Methyl-benzylalcohol |
15.0 |
8.38 |
0.923 |
1.7 |
Aceto-phenone |
16.5 |
9.31 |
0.969 |
1.6 |
Nitrobenzene |
26.4 |
15.50 |
1.190 |
1.9 |
Methyl benzoate |
33.0 |
19.63 |
1.293 |
2.1 |
Test item
|
14.0 |
7.75 |
0.889 |
1.6 |
Equation: log Paw = 1.3361og k' + 0.4093
Result: log Paw = 1.6 at 23°C and at pH = 6.5 (pH of the water used)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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