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EC number: 801-093-8 | CAS number: 1315251-11-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The substance has a lipid normalised BCF value of 513 L/kg at 0.0362 mg/L as determined in a reliable OECD TG 305 study.
Key value for chemical safety assessment
- BCF (aquatic species):
- 513 L/kg ww
Additional information
An OECD TG 305 study in compliance with GLP criteria with Bluegill sunfish (Lepomis macrochirus) is available for the substance. Fish (125/concentration) were exposed to nominal concentrations of 0 (vehicle control), 0.004 and 0.04 mg/L of 14C-labelled the substance under flow-through conditions for 21 days (uptake phase) and followed by 14 days depuration phase. The test concentrations were analytically verified by measuring both total radioactive residue (TRR) and parent substance using GC and were determined as < MQL (vehicle control), 0.00350 and 0.0362 mg/L. Test condition was maintained at 21.5 - 22 ºC and pH 8.1 - 8.5 . The dissolved oxygen concentration was 85 - 101% of saturation value throughout the test. Fish were sampled to measure the concentration of the 14C-labelled test substance as TRR in their tissue. Results: Whole body 14C-residue concentrations reached steady-state equilibrium by 21 days of uptake. The steady state BCF (BCFss) was estimated from the ratio of the steady-state concentration in fish to that in water. The whole fish BCFss was calculated to be 677 L/kg for the low concentration treatment and 884 L/kg for the high concentration treatment. Based on the ratio of the uptake and depuration rate constants (k1 and k2 respectively) the kinetic BCF (BCFk) was estimated at 615 L/kg for the low concentration treatment and 824 L/kg for the high concentration treatment. After lipid normalisation to 5% lipid content, the whole fish BCFk values were 359 L/kg for the low concentration treatment and 513 L/kg for the high concentration treatment. The latter will be used for the risk assessment. The calculated times to 95% depuration of the C14 residue in whole fish tissue were 2.4 and 3.6 days in the low and high treatment groups, respectively.
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