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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Constituent 1
Chemical structure
Reference substance name:
Pseudoephedrine
EC Number:
202-018-6
EC Name:
Pseudoephedrine
Cas Number:
90-82-4
Molecular formula:
C10H15NO
IUPAC Name:
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
Test material form:
solid: crystalline
Details on test material:
- Name of test material (as cited in study report): ( + )-Pseudoephedrine
- Physical state: solid
- Analytical purity: 99.9 %
- Lot/batch No.: 023513AX20

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0 hPa
Remarks on result:
other: extrapolated
Temp.:
25 °C
Vapour pressure:
0 hPa
Temp.:
50 °C
Vapour pressure:
0.008

Any other information on results incl. tables

Measured values:

      Temperature  Vapourpressure,p/hPa

          t/°C                     Cell1                  Cell3

25.1            3.29·10 -4                3.43·10-4

25.2             3.17·10 -4               3.17·10-4

34.7             1.20·10-3                1.25·10 -3

50.8             8.82·10 -3                9.04·10 -3

 

Applicant's summary and conclusion