Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 457-810-6 | CAS number: -
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Test dates: May 25 to May 26, 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The study was conducted according to an internationally recognised method, and under GLP; experimental details are missing, but not considered critical for the assessment. The substance is adequately identified. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 1992
- Deviations:
- not specified
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- GIPC: effective Sep.11, 2003, signed on Jan.23, 2004.
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- -22 °C
- Executive summary:
The melting point of the test substance was determined under GLP according to EU A1 guideline, using differential scanning calorimetry (DSC) method.
Two runs were performed and the mean final temperature was retained.
Under the test conditions the mean onset of melting occured at -22.0°C.
Reference
The DSC analysis was performed twice.
In preliminary test the temperature range for the investigation of the melting point was expected in the range between -80 °C and -20 °C. For both the sample, based on the thermograms, the onset temperature is -22.01 °C and -22.03 °C (mean = -22.02 °C); the peak temperature is -17.68 and -17.54 °C. No significant mass difference was noted before and after performing DSC analysis. The test samples were found to be thermally stable.
Evaluation of endothermic signal for both the samples resulted in mean onset temperature of -22.02 °C. The quality criteria (± 0.5 K) was met and thermogram were reproducible.
Description of key information
Melting point (i.e. transition from solid to liquid) = - 22.0°C (experimental, EU A1, DSC, GLP).
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -22 °C
Additional information
A fully reliable experimental study, conducted according to a recognized EC method and under GLP, is available.
It is considered as a key study, and the result is retained as key data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
