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Diss Factsheets
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EC number: 424-250-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
Test material
- Reference substance name:
- Yellow MGi 1301
- IUPAC Name:
- Yellow MGi 1301
- Test material form:
- solid
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge
Study design
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- Nominal and measured concentrations:
- 10, 32, 100, 320 and 1000 mg/|
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
Any other information on results incl. tables
ln comparison to the inoculum controls the respiration rate of the activated sludge was slightly to moderately inhibited by 15.4, 23.1 and 30.2 % al the three lower nominal YELLOW MGi 1301 concentrations of 10, 32 and 100 mg/|, respectively. At the two higher
nominal YELLOW MGi 1301 concentrations of 320 and 1000 mg/|, the respiration rate reached a plateau with an inhibition rate of 26.6 % for both concentrations. YELLOW MGi 1301 concentrations exceeding 1000 mg/l nominal were not tested. Visual assessment of the appearance of YELLOW MGi 1301 in the final test medium resulted in dark orange solutions without any undissolved particles up to the highest test concentration of 1000 mg/l.
From these inhibition rates, the 3-hour EC50 could not be quantified because up to the highest nominal test concentration of 1000 mg/l less than 50 % inhibition was noted after three hours contact time. Nevertheless, the 3-hour EC50 is clearly higher than 1000 mg/l nominal under the present test conditions. The 3-hour EC20 was calculated by linear regression analysis using the inhibition rates of the 100, 32 and 10 mg/l test concentrations, and was calculated lo be 20.2 mg/l nominal.
The 3-hour EC50 for the positive control 3,5-dichlorophenol, which was tested in the same way as the test article, was found to be 15.2 mg/l and is within the range of 5 - 30 mg/l recommended by the test guidelines; thus, confirming suitability of the activated sludge.
Applicant's summary and conclusion
- Conclusions:
- EC50 (3 h) > 1000 mg/l
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