Registration Dossier
Registration Dossier
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EC number: 913-600-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
No repeated dose toxicity data are available for the reaction mass of sodium iodide, sodium sulfate and sodium chloride. However, for the single components (sodium iodide, CAS 7681-82-5; sodium sulfate, CAS 7757-82-6; sodium chloride, CAS 7647-14-5) toxicity data are existent and the respective substances are already registered.
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
No classification regarding repeated dose toxicity is known for sodium sulfate and sodium chloride. The pharmacological and toxicological mode of action of sodium iodide is determined by iodine. Repeated oral intake of iodine can lead to significant adverse effects on thyroid function and morphology. Therefore, sodium iodide was classified by Bayer HealthCare in 2011 with T, R48/25 according to Directive 67/548/EEC and STOT RE 1, H372 according to Regulation (EC) No. 1272/2008 (CLP).
Since more then 10% of sodium iodide are contained in the reaction mass of sodium iodide, sodium sulfate and sodium chloride also the reaction mass has to be classified with T, R48/25 or STOT RE 1, H372, respectively.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
