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EC number: 923-418-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009/03/16-2009/04/17
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: No amendment to the study plan was requested. No incident, which could have affected the quality or the interpretation of the results obtained, was observed.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 2008/30/04
Test material
- Reference substance name:
- LCE08129:Acetalization products between glucose and C14 alcohol.
- IUPAC Name:
- LCE08129:Acetalization products between glucose and C14 alcohol.
- Details on test material:
- - Identity: LCE08129
- Batch No.: Lot T82925
- Expiration Date: 15-Jul-2010 (retest date)
- Solubility in Water: Emulsifiable
- Aggregate State / Physical Form at
- Room Temperature: Solid
- Storage Conditions: At room temperature at about 20 °C, away from direct sunlight.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- The study was performed with aerobic activated sludge from a wastewater treatment plant (ARA Ergolz II, Füllinsdorf, Switzerland) treating predominantly domestic wastewater.
- Duration of test (contact time):
- ca. 28 d
Initial test substance concentration
- Initial conc.:
- ca. 50 mg/L
- Based on:
- act. ingr.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- The test item was added to the designated test flasks with test water. No emulsifiers or solvents were used.
The sludge was washed twice with tap water by centrifugation and the supernatant liquid phase was decanted. A homogenized aliquot of the final sludge suspension was weighed, thereafter dried and the ratio of wet to dry weight was calculated.
Based on this ratio, calculated amounts of wet sludge were suspended in test water to obtain a concentration equivalent to 4 g (±10%) dry material per liter.
During the holding period of three days prior to use, the sludge was aerated at room temperature.
Prior to use, the sludge was first thoroughly mixed and then diluted with test water to a concentration of 1 g per liter (dry weight basis). Based on the determined dry weight of this diluted activated sludge, defined amounts were added to test water to obtain a final concentration of 30 mg dry material per liter.
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
- Test performance:
- The percent biodegradation of the test item was calculated based on the theoretical oxygen demand (ThOD) of 2.91 mg O2/mg test item.
The biochemical oxygen demand (BOD) of LCE08129 in the test media significantly increased from test start until test termination after 28 days. At the end of the test the mean biodegradation of LCE08129 amounted to 91%.
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 91
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- In the procedure controls, the reference item was degraded by an average of 88% by Day 14, thus confirming suitability of the activated sludge. At the end of the test (Day 28), the reference item was degraded by an average of 94%.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Consequently, LCE08129 was found to be highly biodegradable under the test conditions within 28 days. The pass level for ready biodegradability, i.e. biodegradation of at least 60% of the ThOD in a 10-day window within the 28-day period of the test, was reached.
- Executive summary:
The test item LCE08129 was investigated for its ready biodegradability in a manometric respirometry test over 28 days according to the EU Commission Directive 92/69 EEC, C.4-D Commission Regulation (EC) No 440/2008, C.4-D and the OECD Guideline for Testing of Chemicals No. 301 F.
The percent biodegradation of the test item was calculated based on the theoretical oxygen
demand (ThOD) of 2.91 mg O2/mg test item.
The biochemical oxygen demand (BOD) of LCE08129 in the test media significantly increased from test start until test termination after 28 days. At the end of the test the mean biodegradation of LCE08129 amounted to 91%.
Consequently, LCE08129 was found to be highly biodegradable under the test conditions within 28 days. The pass level for ready biodegradability, i.e. biodegradation of at least 60% of the ThOD in a 10-day window within the 28-day period of the test, was reached.
In the toxicity control, containing both LCE08129 and the reference item sodium benzoate, LCE08129 had no inhibitory effect on the activity of activated sludge microorganisms at the tested concentration of 50 mg/L.
In the procedure controls, the reference item sodium benzoate was degraded by an average of 88% by Day 14, and reached an average biodegradation of 94% by the end of the test (Day 28), thus confirming suitability of the activated sludge.
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