Registration Dossier
Registration Dossier
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EC number: 924-903-2 | CAS number: 1190401-47-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates.
No toxic effects occur at the range of the substances solubility.
LC50 (48) > 100 mg/L (nominal, WAF) for Daphnia magna (OECD 202)
Key value for chemical safety assessment
Additional information
In a GLP guideline study following OECD guideline 202 waterflea (Daphnia magna) were exposed for 48 hours in a static test to Hexamethylene diisocyanate, oligomers, blocked with dibutylamine [BASF SE, 2012]. Based on the low water solubility of the test item the aquatic toxicity was determined by a water accommodated fraction (WAF) and the test was conducted as a limit test with a nominal loading concentration of 100 mg/L substance. No effects on the swimming mobility of daphnia were observed after 48 hours of exposure.
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