4'-aminoazobenzene-4-sulphonic acid

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23.03.2013 -09.04.2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

other: Gravimetric method

Principles of method if other than guideline:

Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Specific details on test material used for the study:

- Name of test material: 4-(4-Aminophenylazo)benzenesulphonic acid
- Molecular formula: C12H11N3O3S
- Molecular weight: 277.303 g/mol
- Smiles notation: S(c1ccc(\N=N\c2ccc(N)cc2)cc1)(O)(=O)=O
- InChl: 1S/C12H11N3O3S/c13-9-1-3-10(4-2-9)14-15-11-5-7-12(8-6-11)19(16, 17)18/h1-8H,13H2,(H,16,17,18)/b15-14+
- Substance type: organic
- Physical state: Solid

Key result

Medium:

methanol

Solubility:

640 mg/L

Temp.:

37 °C

Remarks on result:

other: moderately soluble

Key result

Medium:

other: petroleum ether

Solubility:

360 mg/L

Temp.:

37 °C

Remarks on result:

other: Moderately soluble

Conclusions:

The experimental value of solubility of test chemical in methanol and petrolum ether at 37°C was determined to be 640 mg/L and 360mg/L respectively,indicating that the substance is moderately soluble in methanol and petroleum ether.

Executive summary:

Gravimetric method was used to determine the solubility of the test substance in organic solvent. The experimental value of solubility of test chemical in methanol at 37°C was determined to be 640 mg/L indicating that the substance is moderately soluble in methanol. Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 360 mg/L at 37 °C, indicating that the substance is moderately soluble in petroleum ether. The solubility value of test chemical in methanol at 20°C is equivalent to a value of 345.945 mg/L.

Description of key information

Gravimetric method was used to determine the solubility of the test substance in organic solvent. The experimental value of solubility of test chemical in methanol at 37°C was determined to be 640 mg/L indicating that the substance is moderately soluble in methanol. Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 360 mg/L at 37 °C, indicating that the substance is moderately soluble in petroleum ether. The solubility value of test chemical in methanol at 20°C is equivalent to a value of 345.945 mg/L.

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:

345.945 mg/L

Additional information

Gravimetric method was used to determine the solubility of the test substance in organic solvent. The experimental value of solubility of test chemical in methanol at 37°C was determined to be 640 mg/L indicating that the substance is moderately soluble in methanol. Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 360 mg/L at 37 °C, indicating that the substance is moderately soluble in petroleum ether. The solubility value of test chemical in methanol at 20°C is equivalent to a value of 345.945 mg/L.