Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-572-0 | CAS number: 827-52-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.37 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 3.7 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.037 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 17 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.191 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.019 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.038 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 13.3 mg/kg food
- Assessment factor:
- 300
Additional information
Conclusion on classification
CLP
The environmental hazards of cyclohexylbenzene were evaluated in function of the EU Regulation No. 1272/2008 on the Classification, Labelling and Packaging of Substances andMixtures (CLP).
Relevant toxicity information:
· There is only acute toxicity information available on cyclohexylbenzene. The most sensitive organisms are the invertebrates, presented by an EC50 (48hr) value of 0.37 mg/L forDaphnia magna.
· There is no chronic toxicity information available.
Based on the fact that the acute toxicity information presents an EC50 value < 1 mg/L, cyclohexylbenzene is to be classified for Acute (short-term) aquatic hazard Category 1 (H400: Very toxic to aquatic life). The M-factor for acute toxicity is 1.
Additionally, based on the fact that there is no chronic toxicity data available, Table 4.1.0 (b)(iii) has to be followed to determine the chronic hazard of cyclohexylbenzene. As the acute toxicity is < 1 mg/L, the substance is not readily biodegradable and the experimentally determined log Kow is 5.6 the substance should be classified for Chronic (long-term) aquatic hazard Category 1 (H410: Very toxic to aquatic life with long lasting effects). As there is no chronic toxicity data available, no M-factor for chronic toxicity can be determined.
DSD
The environmental hazards were also evaluated in function of the Dangerous Substances Directive 67/548/EEC (DSD).
Based on the available acute toxicity information (EC50(48hr) = 0.37 mg/L for Daphnia magna), the fact that the substance is not readily biodegradable and the which log Kow is 5.6, the substance should be classified as R50/53.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
