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EC number: 406-640-0 | CAS number: 136920-07-5 KEROFLUX ES 3241
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
oral
rat: LD50 > 2200 mg/kg bw, no mortalities (GLP, OECD 401, BASF 1991)
dermal
rat: LD50 > 2000 mg/kg bw, no mortalities (GLP, OECD 402, BASF 1991)
Key value for chemical safety assessment
Additional information
oral
In an acute oral toxicity limit test following GLP requirements and according to OECD test guideline 401, groups of five fasted, young adult Wistar rats per sex were given a single oral dose of Keroflux ES 3241 (purity not reported) in olive oil at a dose of 2200 mg/kg bw in 5mL/kg bw and observed for 14 days (BASF AG 1991). No mortalities, unregular body weight changes or necropsy findings were observed. Dyspnoe, staggering, piloerection, impaired general state and apathy were the observed reversible clinical signs.The oral LD50 is therefore considered to be >2200 mg/kg bw.
dermal
In an acute dermal limit test following GLP requirements and according to OECD test guideline 402, groups of five young adult Wistar rats per sex were dermally exposed to Keroflux ES 4132 (unchanged; purity not reported) for 24 h under semiocclusive conditions at a dose of 2000 mg/kg bw. Animals then were observed for 14 days. No mortalities, unregular body weight changes, clinical signs, local effects or necropsy findings were observed. The dermal LD50 is therefore considered to be >2000 mg/kg bw.
inhalative
no route of exposure
Justification for classification or non-classification
No classification for acute oral or dermal toxicity according to 67/548/EEC and UN-GHS, respectively, is warranted since no specific signs of toxicity were observed at doses of 2200 or 2000 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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