Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
other:
Title:
ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2)
Year:
2022
Bibliographic source:
ECHA disseminated Dossier of Lithium hydroxide (CAS 1310-65-2), query date 2022-03-09

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 870.1300 (Acute inhalation toxicity)
Qualifier:
according to guideline
Guideline:
EU Method B.2 (Acute Toxicity (Inhalation))
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium hydroxide, monohydrate
EC Number:
603-454-3
Cas Number:
1310-66-3
Molecular formula:
LiOH*H2O
IUPAC Name:
Lithium hydroxide, monohydrate

Test animals

Species:
rat
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: dust
Type of inhalation exposure:
nose only
Duration of exposure:
4 h

Results and discussion

Effect levelsopen allclose all
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 6.15 mg/L air (analytical)
Based on:
test mat.
Remarks:
LiOH monohydrate
Exp. duration:
4 h
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 3.4 mg/L air (analytical)
Exp. duration:
4 h
Remarks on result:
other: calculated for LiOH anhydrous

Applicant's summary and conclusion