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Diss Factsheets
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EC number: 701-341-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence(P, vP)
There are no persistence studies on DPDP; however, there are 2 ready biodegradation studies on TPP, a close analog. Whilst the earlier screening study (Serben 2003) showed poor degradation, the results of this study may have been impacted by the low solubility of TPP. A new and enhanced biodegradation study of TPP (van Ginkel 2015) showed rapid and extensive biodegradation, meeting both the 10 -day window and overall degradation (84% in 28 days) criteria. As such, TPP can be considered as readily biodegradable and not meeting the Annex XIII criteria for persistence. It is reasonable to read these results to DPDP since it chemically very similar to TPP and it too will hydrolyse rapidly in the environment.
Based on the very short half-lives in water and the TPP ready biodegradation test results, DPDP is not expected to meet the criteria for P or vP. The hydrolysis products of DPDP (isodecanol, phenol and phosphorous acid) are readily biodegradable are also do not meet the criteria for P or vP.
Bioaccumulation (B, vB)
Bioaccumulation concentration factor (BCF) cannot not be measured for DPDP due to its rapid hydrolysis. The BCF model estimates for DPDP are generally low, though they may be of limited utility given their wide range and the fact that hydrolysis is not considered in the model. Given the rapid hydrolysis, the bioaccumulation potential of the hydrolysis products, isodecanol, phenol and phosphorous acid, were considered. All are low and well below the criterion for B (bioaccumulative) or vB (very bioaccumulative). As such, it is concluded that DPDP does not meet the criteria for B or vB.
Toxicity (T)
The primary toxicity effect is skin sensitisation; for which DPDP is classified. Based on DPDP’s low water solubility and rapid hydrolysis, it is not anticipated to cause aquatic toxicity based on the amount and relatively aquatic toxicity of its hydrolysis products. Its mains hydrolysis product, phenol, is now classified as Aquatic Chronic 2 (H411). As such, this same classification is being adopted for DPDP.
PBT/vPvB criteria and justification
DPDP is not classifiable as a PBT or a vPvB substance as it does not meet criteria for either persistence or bioaccumulation.
It should be noted that the ECB PBT Working Group review diisodecyl phenyl phosphite (DDPP), a related substance, and the conclusion from their assessment was that DDPP is not a PBT or vPvB substance based on hydrolysis. This conclusion should also be applicable to DPDP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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