Registration Dossier
Registration Dossier
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EC number: 478-900-1 | CAS number: 6156-18-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
2,2-bis(methylthio)propane was found to be toxic for Daphnia magna.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.9 mg/L
Additional information
The acute toxicity of 2,2-bis(methylthio)propane to Daphnia magna has been investigated through OECD Guideline 202 and according to GLP requirements (Gancet, 2008). The immobility of the Daphnia was determined in a static 48-hour test by visual observation after 24 and 48 hours.The final concentrations of the test substance were not maintained within the designated limit of 80 % of the initial concentrations in test flasks. Therefore the results are based on the measured concentrations in the test vessels. The EC50 -48h based on actual mean concentrations was 2.9 mg/L. All the validity criteria were fulfilled.
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