3-(2-methoxy-5-methylphenyl)-3-phenylpropanoic acid

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From August 29th, 2018 to August 31st, 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Key result

Boiling pt.:

376.9 °C

Atm. press.:

ca. 1 010 hPa

Decomposition:

yes

Decomp. temp.:

376.9 °C

In the preliminary study, the initial average boiling point value was approximately 388.0ºC. In the main study, the following average values of boiling temperature (measured) and boiling point (corrected according to barometric pressure) were obtained:

Table 1. Summary of test results.

Sample	Atmospheric pressure, hPa	Boling temperature, ºC	Boiling point, ºC
1	1011.2	380.1	380.2
2	1008.2	376.6	376.9
3		373.3	373.5
Average values ± standard deviations, ºC		376.7 ± 3.4	376.9 ± 3.4

Simultaneously with boiling, a decomposition process took place: in all three samples, a change in color from transparent to brown was observed.

Conclusions:

The boiling point of the test item was determined to be 376.9 ± 3.4ºC (at 1010 hPa). The boiling process took place together with thermal decomposition.

Executive summary:

The determination of the boiling point of the test item was carried out according to OECD 103 and EU method A.2 (method according to Siwoloboff), under GLP conditions. A preliminary study was performed in order to determine the boiling temperature range. Based on the results of this test (approx. value of 388ºC), a final test consisting of three series of measurements in the range of 360 - 400ºC heated at a rate of 1.0ºC/min was performed. The study was performed under atmospheric pressure of 1011.2 and 1008.2 hPa. The boiling point of the test item, which took place toghether with thermal descomposition, was determined to be 376.9 ± 3.4ºC (at 1010 hPa).

Description of key information

Key study. Method according to OECD 103 / EU Method A.2 (Siwoloboff method), GLP study. The boiling point of the test item, which occurs with thermal decomposition, is 376.9 ± 3 ºC (at 1011.2 hPa).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

376.9 °C