Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,2-dihydro-2-oxoquinoline-4-carboxylic acid
EC Number:
239-827-9
EC Name:
1,2-dihydro-2-oxoquinoline-4-carboxylic acid
Cas Number:
15733-89-8
Molecular formula:
C10H7NO3
IUPAC Name:
1,2-dihydro-2-oxoquinoline-4-carboxylic acid
Test material form:
solid: particulate/powder

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
25 °C
pH:
7
Remarks on result:
not determinable
Details on results:
The partition coefficient of the hydroxy acid can't be calculated. The molecule is not retained in the recommended HPLC method.
Based on the retention time observed with the selected referrences, the partition coefficient is less than the partition coefficient of the methylethylketone (0.3).

Applicant's summary and conclusion

Conclusions:
The partition coefficient is evaluated according OECD117 method. The hydroxy acid can't be calculated. The molecule is not retained in the recommended HPLC method.
Based on the retention time observed with the selected referrences, the partition coefficient is less than the partition coefficient of the methylethylketone (0.3).
Executive summary:

The partition coefficient is evaluated according OECD117 method. The hydroxy acid can't be calculated. The molecule is not retained in the recommended HPLC method.

Based on the retention time observed with the selected referrences, the partition coefficient is less than the partition coefficient of the methylethylketone (0.3).