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EC number: 202-908-4 | CAS number: 101-02-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According to guideline and GLP with deviation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- yes
- Remarks:
- Instead of a centrifuged sludge a settled sludge was used.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Triphenyl phosphite
- EC Number:
- 202-908-4
- EC Name:
- Triphenyl phosphite
- Cas Number:
- 101-02-0
- Molecular formula:
- C18H15O3P
- IUPAC Name:
- triphenyl phosphite
- Details on test material:
- - Physical state: liquid
- Storage condition of test material: room temperature
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Details on test solutions:
- Vessels: 250 ml BOD flasks with gas inlet
Water: Dechlorinated drinking water
Temperature: 20 ± 2°C
Nutrient solution:
16 g Peptone
11 g Meat extract
3.0 g Urea
0.7 g NaCI
0.4 g CaCl2 x 2 H20
0.2 g MgSO4 x 7 H20
2.8 g K2HP04
were dissolved and the volume made up to one liter with dechlorinated drinking water.
Remarks : 6.4 ml of the nutrient solution, 74 ml water, 40 ml of the stock solutions and 80 ml of the sludge were mixed in 250 ml BOD flasks and aerated immediately.
Stock solution and test solutions
499.8 mg test substance were mixed with 500 ml water by polytron for 5 minutes and made up to 1000 ml with water. (stock solution 500 mg/l for testconcentration 100 mg/l)
320 ml of the stock solution 500 mg/l were mixed and made up to 1000 ml with water, (stock solution 160 mg/l for test concentration 32 mg/l).
100 ml of the stock solution 500 mg/l were mixed and made up to 1000 ml with water (stock solution 50 mg/l for test concentration 10 mg/l).
100 ml of stock solution 160 mg/l were mixed and made up to 1000 ml with water, (stock solution 16 mg / I for testconcentration 3.2 mg/l).
100 ml of stock solution 50 mg/l were mixed and made up to 1000 ml with water, (stock solution 5 mg/l for test concentration 1 mg/l).
The stock solutions were freshly prepared at the start of the test
Test organisms
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- Activated sludge collected from the sewage treatment plant of CH-4153 Reinach on 06/02/95. The pH after collection was 7.6. The selected sewage work is treating predominantly domestic sewage. The preparation w^as carried out according to the method described in the guideline. The sludge was separated from the aqueous layer by settling instead of centrifugation. The pH of the sludge before use was 8.0.
Study design
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- Test temperature:
- 20+-2°C
- pH:
- 8.2-8.4
- Dissolved oxygen:
- Oxygen consumption per hour in mg/liter with a ORION - Electrode Type 97- 08, ORION Microprocessor lonalizer 901 and plotted on a recorder.
- Nominal and measured concentrations:
- Test substance : 100.0, 32.0,10.0, 3.2 and 1.0 mg/l
Reference substance : 32.0,10.0 and 3.2 mg/l - Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 3 h
- Dose descriptor:
- other: EC20
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Results with reference substance (positive control):
- EC50(3h) = 11.8 mg/l
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.