Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 944-090-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 15, 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- ebulliometer
- Boiling pt.:
- 38 °C
- Atm. press.:
- 58 kPa
- Boiling pt.:
- 63 °C
- Atm. press.:
- 201 kPa
- Boiling pt.:
- 70 °C
- Atm. press.:
- 266 kPa
- Boiling pt.:
- 76 °C
- Atm. press.:
- 337 kPa
- Boiling pt.:
- 80 °C
- Atm. press.:
- 404 kPa
- Boiling pt.:
- 85 °C
- Atm. press.:
- 485 kPa
- Boiling pt.:
- 88 °C
- Atm. press.:
- 546 kPa
- Boiling pt.:
- 93 °C
- Atm. press.:
- 661 kPa
- Boiling pt.:
- 97 °C
- Atm. press.:
- 748 kPa
- Boiling pt.:
- 98 °C
- Atm. press.:
- 822 kPa
- Boiling pt.:
- 102 °C
- Atm. press.:
- 887 kPa
- Boiling pt.:
- 103 °C
- Atm. press.:
- 929 kPa
- Boiling pt.:
- 106 °C
- Atm. press.:
- 1 022 kPa
- Key result
- Boiling pt.:
- ca. 105.6 °C
- Atm. press.:
- 101.325 kPa
- Remarks on result:
- other: Calculated with the Clapeyron-Clausius equation
- Conclusions:
- The boiling point of the reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) was reported to be 105.6°C at 101.325 kPa
- Executive summary:
The boiling point and latent heat of evaporation of the reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) was assessed in a study undertaken according to OECD Guideline 103 (Boiling Point) without any reported deviation. This method required the use of an ebulliometer, with measurements of the boiling point temperature taken at an absolute pressure (above the sample) range of 58 to 1022 kPa. The Clapeyron-Clausius equation was applied to calculate an ultimate boiling point temperature of 105.6 °C and latent heat of evaporation of 41.0 kJ/mol at the required standard pressure of 101.325 kPa.
Reference
Latent heat of evaporation of the sample was 41.0 kJ/mol.
Description of key information
A boiling point temperature of 105.6 °C at 101.325 kPa was calculated for the reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1).
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 105.6 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.