Registration Dossier
Registration Dossier
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EC number: 203-653-1 | CAS number: 109-17-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Review of the toxicity of multifunctional acrylates
- Author:
- Andrews LS and Clary JJ
- Year:
- 1 986
- Bibliographic source:
- J. Toxicol. Environ. Health 19(2):149-64
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The dermal LD50 of the substance has been determined to evaluate the potential of acute toxicity.
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 3,6,9-trioxaundecamethylene dimethacrylate
- EC Number:
- 203-653-1
- EC Name:
- 3,6,9-trioxaundecamethylene dimethacrylate
- Cas Number:
- 109-17-1
- Molecular formula:
- C16H26O7
- IUPAC Name:
- 3,6,9-trioxaundecamethylene dimethacrylate
- Details on test material:
- no data available
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Type of coverage:
- not specified
- Doses:
- 3000 mg/kg
- Control animals:
- not required
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 3 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The dermal LD50 value of PEG-4 Dimethacrylate in the rabbits was > 3000 mg/kg.
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