Registration Dossier
Registration Dossier
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EC number: 695-101-5 | CAS number: 1275611-65-8
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. Therefore no chronic fish testing is required.
Key value for chemical safety assessment
Additional information
The safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. Therefore no chronic fish testing is required. In addition, fish are in general less sensitive to cationic surfactants as observed for linear alkyl diamines or quats compared to algae and daphnia.
For the calculation of the PNECaquatic it is therefore considered unlikely that fish toxicity will be critical for N-C16-18-alkyl-(evennumbered, C18 unsaturated) trimethylpropane-1,3-diamine. Hence any additional long-term toxicity testing with fish will not add scientific value to the ecotoxicity profile of this substance other than for obtaining a lower assessment factor. It is therefore concluded that for scientific reasons and in accordance to REACH legislation further testing on fish has to be avoided for reasons of animal welfare and that based on the weight of evidence available and the ecotoxicity data for several cationic surfactants a safety factor of 50 will be applied for the derivation of the PNECaquatic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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