Registration Dossier
Registration Dossier
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EC number: 271-896-0 | CAS number: 68611-47-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 425 (Acute Oral Toxicity: Up-and-Down Procedure)
- GLP compliance:
- yes (incl. QA statement)
- Test type:
- up-and-down procedure
Test material
- Reference substance name:
- Silicic acid (H4SiO4), zinc salt (1:2), manganese-doped
- EC Number:
- 271-896-0
- EC Name:
- Silicic acid (H4SiO4), zinc salt (1:2), manganese-doped
- Cas Number:
- 68611-47-2
- Molecular formula:
- Zn2SiO4:Mn
- IUPAC Name:
- Silicic Acid (H4SiO4), Zinc Salt (1: 2), Manganese-Doped
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Doses:
- 175, 230, 310, 410, 550 and 2000 mg kg-1 of body weight
- No. of animals per sex per dose:
- 6
- Control animals:
- no
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- no
- Clinical signs:
- other: no signs of toxicity
- Gross pathology:
- No animal presented compound-related macroscopic findings on gross necropsy.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
