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EC number: 276-127-2 | CAS number: 71873-51-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- adopted 1984
- GLP compliance:
- not specified
- Details on test solutions:
- - Appearance: clear, yellow solution.
- Preparation: test item was dissolved in the test medium at a concentration of 100 mg/100 ml (stock solution). Thereafter, series of sequential dilutions with the test medium were prepared to obtain the flnal test concentrations of the test article. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: the animals were bred in the testing laboratories of under standardized conditions.
- Age of animals: for the tests, animals with an age of less than 24 hours were used. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
- pH:
- Start: 8.4
End: 8.3 - Dissolved oxygen:
- Start: 8.5 mg/l
End: 8.7 mg/l - Nominal and measured concentrations:
- 1, 10 and 100 mg/l, nominal
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 50 ml beakers containing 20 ml of test medium.
- No. of organisms per vessel: 10 animals.
- No. of vessels per concentration: 2 replicates.
- No. of vessels per control: 2 replicates.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: the test medium used was prepared according to the Directive EEC. The water used was bi-distilled water.
- CaCl2 × 2H2O: 294 mg/l
- MgSO4 × 7 H2O: 123 mg/l
- NaHCO3: 65 mg/l
- KCl: 5.8 mg/l
OTHER TEST CONDITIONS
- Adjustment of pH: adjusted to 7.9 ± 0.3.
- Photoperiod: 16 hours of illumination.
- Light intensity: 1000 Lux.
EFFECT PARAMETERS MEASURED
Test evaluations were done according to the OECD guideline 202 by visual control of the mobility of the daphnids after 24 hours.
VALIDITY OF THE TEST
The validity of the test was proven by determining the mortality of the control animals tested under the same conditions. - Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- EC0 (24h): 10 - 100 mg/l (nominal)
EC100 (24h) > 100 mg/l (nominal) - Conclusions:
- EC50 (24h) > 100 mg/l (nominal)
- Executive summary:
The toxicity study was run using the species Daphnia magna. The daphnids were exposed over a period of 24 hours to the test article in 20 ml beakers containing 20 ml test medium per 10 animals. All tests were run in duplicate. The concentrations tested were 0, 1, 10 and 100 mg/l nominal.
10 % of daphnids resulted to be immobilized after 24 hours in one of the vessels containing 1 mg/l; at the concentration of 10 mg/l, no immobilization was recorded; at 100 mg/l, 10 and 20 % of immobilization was recorded.
Conclusion
EC50 (24h) > 100 mg/l (nominal)
Reference
Influence of test item on the immobilization of Daphnia magna.
Vessel | No animals | No of response | % of response |
Control | 10 | 0 | 0 |
Control | 10 | 0 | 0 |
Test item 1 mg/l | 10 | 0 | 0 |
Test item 1 mg/l | 10 | 1 | 10 |
Test item 10 mg/l | 10 | 0 | 0 |
Test item 10 mg/l | 10 | 0 | 0 |
Test item 100 mg/l | 10 | 1 | 10 |
Test item 100 mg/l | 10 | 2 | 20 |
Description of key information
EC50 (24h) > 100 mg/l, nominal
Key value for chemical safety assessment
Additional information
The toxicity potential of Acid Yellow 218 to invertebrates was assayed in Daphnia magna. The daphnids were exposed over a period of 24 hours to the test artlcle nominal concentrations of 0, 1, 10 and 100 mg/l. 10 % of daphnids resulted to be immobilized after 24 hours in one of the vessels containing 1 mg/l; at the concentration of 10 mg/l no immobilization was recorded; while at 100 mg/l 10 and 20 % of immobilization was recorded.
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