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EC number: 612-975-5 | CAS number: 6225-08-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
After 7 and 14 days of exposure to Genagen PA, no significant inhibition of the microbial nitrate transformation was observed for the test item concentrations 62.5 and 125 mg/kg soil dry weight. For the test item concentrations 250, 500 and 1000 mg/kg soil dry weight, negative nitrate formation rate were determined, due to low nitrate contents.
After 28 days of exposure, no significant inhibition of the microbial nitrate transformation was observed for the test item concentrations 62.5, 125 and 250 mg/kg soil dry weight. For the test item concentrations 500 and 1000 mg/kg soil dry weight, negative nitrate formation rate were determined.
For calculation of the ECx-values, the inhibition was set as 100 % for concentrations with negative nitrate-N formation rates.
After 7 days of exposure the EC10-, EC25- and EC50-values for inhibition of the nitrate-N formation rate were 130, 137 and 151 mg/kg soil dry weight, respectively.
After 14 days of exposure the EC10-, EC25- and EC50-values for inhibition of the nitrate-N formation rate were 162, 173 and 192 mg/kg soil dry weight, respectively.
After 28 days of exposure the EC10-value for inhibition of the nitrate-N formation rate in soil was 268 mg/kg soil dry weight, the EC25-value was 284 mg/kg soil dry weight and the EC50-value was 311 mg/kg soil dry weight.
The corresponding no-observed effect concentration (NOEC) was 125 mg Genagen PA/ kg soil dry weight on day 7 and 14 and 250 mg Genagen PA/kg soil dry weight on day 28. The LOEC was determined to be 250 mg Genagen PA/kg soil dry weight after 7 and 14 days and 500 mg Genagen PA/ kg soil dry weight after 28 days of exposure.
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 268 mg/kg soil dw
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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