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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Under the conditions of this acute fish toxicity study on Zebra-fish (Brachydanio rerio) the observed and calculated endpoints for the effect of ZEH 2017 were the followings:
The 24h, 48h, 72h and 96h LC50 value: > 100 mg/L (nominal)
The 96h LC100 value: > 100 mg/L (nominal)
The 96h No-Observed Effect Concentration (NOEC): 100 mg/L (nominal)
The 96h Lowest Observed Effect Concentration (LOEC): > 100 mg/L (nominal)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
100 mg/L

Additional information

A study was conducted to assess the acute toxicity of the test substance to Zebra fish ( Brachydanio rerio) in accordance with the OECD Guideline 203. A limit test with 4 fishes per group was conducted at concentrations of 0.1, 1, 10 and 100mg/L. No mortality was observed and a limit test at 100mg/L was done with seven fish and 5 liter test solution for both the control group and the test group. The total test period was 96 h and samples for analytical confirmation of actual exposure concentrations were taken at the start and the end of the test. Measured concentration was 95.0 mg/L at the start and 95.3 mg/L at the end of the test.

All achievable validity criteria were met during this study.

Under the conditions of this acute fish toxicity study on Zebra-fish (Brachydanio rerio) the observed and calculated endpoints for the effect of ZEH 2017 were the following:

  • The 24h, 48h, 72h and 96h LC50 value: > 100 mg/L (nominal)
  • The 96h LC100 value: > 100 mg/L (nominal)
  • The 96h No-Observed Effect Concentration (NOEC): 100 mg/L (nominal)
  • The 96h Lowest Observed Effect Concentration (LOEC): > 100 mg/L (nominal)