Registration Dossier
Registration Dossier
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EC number: 234-808-1 | CAS number: 12034-57-0
Endpoint summary
Administrative data
Description of key information
Fish:
During the limit test conducted by Scheerbaum (2003) according to EU.C.1 with Nobium(II)-Oxide, no acute toxic to zebrafish (Danio rerio) were observed in saturated solution. The measured content of Niobium was < 1 mg/L (nominal loading 100 mg/L).
These results are supported by Lili (2005) who investigated the acute toxicity of the test item to zebrafish according to OECD Guideline 203 at several concentrations up to 100 mg/L using an emulsifier.
It can be concluded that the NOEC for 96h exposure of the test item to zebrafish is above 1 mg/L (measured concentration).
Aquatic Invertebrates:
The 48-h acute immobilisation test of Niobium(II)-Oxide to Daphnia magna was conducted under static conditions at the saturated solution level in accordance with the EC Directive 92/69/EC method C.2. No biological significant effect was observed.
Aquatic Algae:
In a 72-h acute toxicity study, the cultures of Desmodesmus subspicatus were exposed to Niobium(II)-Oxide at the saturated solution level under static conditions in accordance with the EC Directive 92/69/EC, C.3. Niobium(II)-Oxide was found not to inhibit the biomass growth and growth rate of the freshwater green alga D. subspicatus.
Microorganisms:
A Respiration Inhibition Test with activated sludge was performed for 3 h with the test item Niobium(II)-Oxide in accordance with the OECD Guideline 209 (1984). Results show that the test item is not toxic at concentrations ≤1000 mg/L to activated sludge of a municipal sewage treatment plant.
Additional information
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