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EC number: 310-028-8 | CAS number: 102110-29-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Boric acid (H3BO3), solid soln. with strontium oxide, europium-doped
- EC Number:
- 310-028-8
- EC Name:
- Boric acid (H3BO3), solid soln. with strontium oxide, europium-doped
- Cas Number:
- 102110-29-2
- Molecular formula:
- SrB4O7:Eu
- IUPAC Name:
- Boric acid (H3BO3), solid soln. with strontium oxide, europium-doped
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsored by ZHEJING JINGNENG PHOSPHOR MATERIAL CO., LTD. ; 170825
- Expiration date of the lot/batch: 24 Aug 2019
- Purity: 99%
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room Temperature, protected from light
- Stability under test conditions: not specified
- Solubility and stability of the test substance in the solvent/vehicle: Insoluble in water, soluble in the inorganics acid
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: The test item has been prepared at 1000 mg/L, 100 mg/L and 10 mg/L in culture medium. The solutions have been extracted for 72 h at room temperature. From extract at 10 mg/L two solutions have been prepared (1 mg/L and 0.1 mg/L) under stirring.
- Final dilution of a dissolved solid, stock liquid or gel: ten-fold dilutions
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: The test item has been prepared at 1000 mg/L, 100 mg/L and 10 mg/L in culture medium. The solutions have been extracted for 72 h at room temperature. From extract at 10 mg/L two solutions have been prepared (1 mg/L and 0.1 mg/L) under stirring.
- Evidence of undissolved material (e.g. precipitate, surface film, etc.): In the bottom of the beaker some particle was visible
- Evidence of undissolved material (e.g. precipitate, surface film, etc.): In the 1000 mg/L extract in the bottom of the beaker some particle was visible.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain/clone: Daphnia magna straus, Crustacean, Cladocero
- Justification for species other than prescribed by test guideline: Daphnia magna straus has been used for this test because is one of the recommended specie in OECD 202.
- Age: 6-24 hours
- Feeding during test
- Food type: Green alga Pseudokirchneriella subcapitata and Saccharomices cerevisiae
- Amount: None during the course of the test.
- Frequency: None during the course of the test.
ACCLIMATION
- Acclimation conditions (same as test or not) : same as test
- Type and amount of food:Green alga Pseudokirchneriella subcapitata and Saccharomices cerevisiae
- Feeding frequency: not specified
- Health during acclimation (any mortality observed): healthy
Study design
- Test type:
- static
- Water media type:
- other: Reconstituted dilution water
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- Daphnia have been kept without light, aeration and feeding for the whole length of the assay.
Test conditions
- Hardness:
- 140- 250 mg CaCO3/L
- Test temperature:
- 20°C ± 2°C
- pH:
- 7.7 - 8.0
- Dissolved oxygen:
- > 3 mg/L
- Nominal and measured concentrations:
- Range finding test : 1000 mg/L, 100 mg/L, 10 mg/L, 1 mg/L and 0.1 mg/L ( nominal concentration)
Definitive test: 100 mg/L (nominal concentration) - Details on test conditions:
- TEST SYSTEM
- Test vessel: Glass Beaker (500 ml).
- Material, size, headspace, fill volume: Glass, 500 mL
- Aeration: no
- Renewal rate of test solution (frequency/flow rate): static
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- No. of vessels per vehicle control (replicates): 5
- Biomass loading rate: not specified
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: 25 mL of solution A, B, C and D have been taken to 1000 mL volume with deionised water.
- Culture medium different from test medium: no
OTHER TEST CONDITIONS
- Adjustment of pH:not specified
- Photoperiod: None during the course of the test.
- Light intensity: None during the course of the test.
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : If the organisms, after light stirring of the vessels, were not capable to move in the following 15 seconds.
RANGE-FINDING STUDY
- Test concentrations: 1000 mg/L, 100 mg/L, 10 mg/L,1 mg/L, 0.1 mg/L
- Results used to determine the conditions for the definitive study: After the results of the range finding test, a limit test has been performed.
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- mobility
- Details on results:
- - Mortality of control: none
- Other adverse effects control: not specified
- Abnormal responses: no - Reported statistics and error estimates:
- No deviation has been detected during the study.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The immobilisation of control animals must not be higher than 10% at the end of the test. The concentration of dissolved oxygen in the vessels ought to be higher than 3 mg/L during the assay.
- Conclusions:
- The obtained results, in compliance with assay validity criteria, showed that Daphnia magna EC50 after 48 hours of the nominal concentration of the test item “Boric acid (H3BO3), solid soln. with strontium
oxide, europium-doped” is >100 mg/L. - Executive summary:
The 48 hr-acute toxicity of Boric acid (H3BO3), solid soln. with strontium oxide, europium-doped to Daphnia magna was studied under static conditions according to OECD guideline N.202 . During the range finding test, the organisms have been exposed to 5 different dilutions of the test item for 48 hours. After the results of the range finding test, a limit test has been performed. The organisms have been exposed to 100 mg/L of the test item for 48 hours. Mortality/immobilization were observed daily. Based on the result, the 48 hour EC50 was more than 100 mg /L (nominal).
This study is classified as acceptable and satisfies the guideline requirements for an acute toxicity study with freshwater invertebrates.
Results Synopsis
Test Organism Age (e.g. 1stinstar): 6-24 hours
Test Type (Flowthrough, Static, Static Renewal): Static
EC50: >100 mg/L (nominal)
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