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EC number: 260-690-6 | CAS number: 57352-34-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment
BCFBAF model (v3.01) of Estimation Programs Interface (EPI Suite, 2017) was used to predict the bioconcentration factor (BCF) of test chemical Ethylbenzenesulphonic acid (CAS No. 57352 -34 -8). The bioconcentration factor (BCF) of Ethylbenzenesulphonic acid was estimated to be 3.162 L/kg whole body w.w (at 25 deg C) which does not exceed the bio concentration threshold of 2000, indicating that the chemical Ethylbenzenesulphonic acid is not expected to bioaccumulate in the food chain.
Additional information
Bioaccumulation: aquatic / sediment
Various predicted data for the target compound Ethylbenzenesulphonic acid (CAS No. 57352-34-8) and supporting weight of evidence study for its read across substance were reviewed for the bioaccumulation end point which are summarized as below:
In aprediction done using theBCFBAF Program(v3.01) of Estimation Programs Interface (EPI Suite, 2017) was used to predict the bioconcentration factor (BCF) of test chemical Ethylbenzenesulphonic acid (CAS No. 57352 -34 -8). The bioconcentration factor (BCF) of Ethylbenzenesulphonic acid was estimated to be 3.162 L/kg whole body w.w (at 25 deg C).
In an another prediction done by using Bio-concentration Factor (v12.1.0.50374) moduleACD (Advanced Chemistry Development)/I-Lab predictive module, 2017), theBCF of the test substance Ethylbenzenesulphonic acid was estimated to be 1.99 and 1 at pH range 0 & 1-14, respectively.
Bioconcentration Factor (BCF) of test chemical Ethylbenzenesulphonic acid was estimated using Chemspider database(ChemSpider, 2017). The bioconcentration factor of test substance Ethylbenzenesulphonic acid was estimated to be 1 at both pH 5.5 and 7.4, respectively.
In a supporting weight of evidence study from authoritative database (HSDB, 2017) for the read across chemical Benzenesulphonic acid (CAS no. 98-11-3),bioaccumulation experiment was conducted for estimating the BCF (bioaccumulation factor) value of read across chemical Benzenesulphonic acid. The bioaccumulation factor (BCF) value was calculated using a log Kow of -2.25 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of Benzenesulphonic acid was determined to be 1.15 dimensionless.
For the read across chemical 2-amino-5-methylbenzenesulfonic acid (CAS no. 88-44-8),bioaccumulation study was conducted on test organism Cyprinus carpio for 6 weeks for evaluating the bioconcentration factor (BCF value) of 2-amino-5-methylbenzenesulfonic acid (J-CHECK, 2017). The study was performed according to other guideline "Bioaccumulation test of a chemical substance in fish or shellfish" provided in "the Notice on the Test Method Concerning New Chemical Substances", respectively. Cyprinus carpio was used as a test organism for the study. Test chemical nominal conc. used for the study were 2mg/l and 0.2mg/l, respectively. Range finding study involve the TLm (48 hr) 480 mg/l (w/v) on Rice fish (Oryzias latipes).The bioconcentration factor (BCF value) of substance 2-amino-5-methylbenzenesulfonic acid on Cyprinus carpio was determined to be ≤ 0.4 L/Kg at a conc. of 2mg/l and ≤ 4.0 L/Kg at a conc. of 0.2mg/l, respectively.
On the basis of above results for target chemical Ethylbenzenesulphonic acid (from EPI suite, ACD labsand ChemSpider, 2017) and for its read across substance from authoritative database (HSDB and J-CHECK, 2017), it can be concluded that the BCF value of test substance Ethylbenzenesulphonic acid ranges from 1– 3.162 which does not exceed the bioconcentration threshold of 2000, indicating that the chemical Ethylbenzenesulphonic acid is not expected to bioaccumulate in the food chain.
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