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EC number: 267-500-0 | CAS number: 67874-72-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity to aquatic algae is based on read-across from the close structural analogue Verdox (CAS# 20298-69-5). The 72 -h ErC50 and NOErC values are converted to Coniferan and are 4.0 mg/L and 0.54 mg/L, respectively.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 4 mg/L
- EC10 or NOEC for freshwater algae:
- 0.54 mg/L
Additional information
For the read-across source chemical Verdox the effect on the growth of aquatic algae was determined in a GLP-compliant OECD Guideline 201 study. Green algae (Desmodesmus subspicatus) with an initial cell concentration of 4E+03 cells/mL) were exposed for 72 hours to nominal concentrations of 1.75, 3.5, 7.0, 14, and 27 mg/L Verdox (3 replicates per concentration) and a control (6 replicates). Inhibition of algal growth rate and biomass (as yield) were monitored and all cultures were inspected microscopically at 72 hours. Samples of the test solutions were taken 0 and 72 hours and analysed by gas chromatography (GC). As the measured concentrations declined over the 72-hour testing period, the geometric mean of measured concentrations was used for calculating effect concentrations. The final concentration were all below the LoQ. Both growth rate and yield were significantly reduced compared to controls (p<0.05) at the three highest test levels. Based on these reductions the 72- h ErC50 and the 72-h NOErC were determined to be 4.2 and 0.57 mg/L, respectively. These effect concentrations are over-conservative values, because the LoQ is driving these toxicity values. No attempt has been made to calculate more realistic values because for the enviromental risk characterisation the algae NOEC of 0.57 mg/l because will not be the key value for the PNEC derivation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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