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EC number: 689-267-8 | CAS number: 501925-98-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
In the acute immobilisation test with Daphnia magna (STRAUS), the effects of the Water Accommodated Fraction (WAF) with the nominal loading of 100 mg/L of the test item were determined according to OECD 202 (2004) and Council Regulation (EC) No. 440/2008 Method C.2 (2008) over a period of 48 hours. 100 mg/L of the test item were shaken with dilution water at 20 rpm for 24 hours at room temperature . After a 1-h settlement period, the test item phase was separated by siphon and the test organisms exposed to the clear aqueous phase. Twenty daphnids were exposed to the WAF and the control.
The tested WAF with a nominal loading of 100 mg/L of the test item and the control were analytically verified by analysis of dissolved organic carbon at the start of the exposure (0 h) and at the end of the exposure (48 h). The measured concentrations of dissolved organic carbon in the control were < 2.00 mg C/L. The measured concentrations of dissolved organic carbon in the WAF with the nominal loading of 100 mg/L were 38.1 mg C/L (0 h) and 40.1 mg C/L (48 h). Exposures are expressed in terms of the original concentrations of the test item in water at the start of the mixing period (loading rate). Water quality parameters measured at the start (0 h) and at the end of the exposure (48 h), were within the acceptable limits. The validity criteria of the test guidelines were fulfilled.
At a nominal loading of 100 mg/L, no effects were observed on Daphnia magna. The key value reads as follows: EL 50 > 100 mg/L.
The toxicity of the test substance to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to OECD 201. The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours.
The study was conducted under static conditions with an initial cell density of 4332 cells/mL. Five water accommodated fractions (WAF) were prepared with a nominal loading of 10.0 - 20.0 - 40.0 - 80.0 - 160 mg test item/L. Three replicates were used for each water accommodated fraction and six for the control. The environmental conditions were within the acceptable limits. All test loadings and the control were analytically verified via analysis of dissolved organic carbon measured as NPOC (Non Purgeable Organic Carbon) at the start and the end of the exposure. All effect values given are based on nominal test item loadings of the test item.
In this study inhibition on growth of the freshwater green alga Desmodesmus subspicatus was found after 72 hours exposure to the test item. The nominal EL50-values for inhibition of growth rate (ErL50) after 72 hours was > 160 mg/L. The nominal NOEL-values for inhibition of growth rate after 72 hours was 40.0 mg/L. All effect values given are based on nominal test item loadings.
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