Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

KEY PARAMETERS FOR CLASSIFICATION

The registered (parent) substance methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432 -65 -7) hydrolyses rapidly in contact with water under environmentally relevant conditions. Therefore, the environmental hazard and risk assessment is based on the silanol hydrolysis product, i.e. methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate. The other, alcohol hydrolysis product, methanol, is not expected to affect the environmental hazard profile of the parent substance.

 

Abiotic degradation - Hydrolysis

DT50 = 1.9 h (20 -25°C and pH 7, QSAR)

 

Biodegradation in water

Not readily biodegradable (15.5 - 19.5% biodegradation after 28 d, OECD 301F)

 

Bioaccumulation

log Kow (parent) = 1.1 (QSAR)

log Kow (silanol hydrolysis product) = -1.9 (QSAR)

 

Aquatic acute toxicity

Fish

LC50 (96 h) >100 mg/L (nominal, OECD 203, Oncorhynchus mykiss)

Aquatic invertebrates

EC50 (48 h) > 100 mg/L (nominal, OECD 202, Daphnia magna)

Algae

ErC50 (72h) = 117.42 mg/L (nominal, OECD 201, Desmodesmus subspicatus)

 

Aquatic chronic toxicity

Fish

no data available

Aquatic invertebrates

no data available

Algae/aquatic plant

NOErC (72 h) = 33.5 mg/L (nominal, OECD 201, Desmodesmus subspicatus)

 

Classification according to CLP

Methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432 -65 -7) hydrolyses rapidly under environmental conditions (DT50 = 1.9 h, at pH 7 and 20 - 25 °C) to form the hydrolysis product methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate and methanol. The parent substance methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate is not considered to be readily biodegradable (OECD 301F). Based on the rapid hydrolysis of the parent substance and the duration of the biodegradation study, it can be assumed that mainly the hydrolysis products methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate and methanol were present. The alcohol hydrolysis product methanol is known for its readily biodegradation (OECD SIDS, 2004). Therefore, the silanol hydrolysis product methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate is considered to not be readily biodegradable.

Acute toxicity data for the parent substance methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate are available for all three trophic levels (fish, aquatic invertebrates, algae). All LC/EC50 effect values are >100 mg/L. Due to the duration and exposure scenario of the performed short-term toxicity studies (static set-up) and the rapid hydrolyses of the parent substance, it can be assumed that the organisms were mainly exposed to the hydrolysis products. On this basis, the parent substance methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432 -65 -7) does not need to be classified and labeled according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).