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EC number: 245-890-3 | CAS number: 23787-90-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The effect of the test item on the growth of Pseudokirchneriella subcapitata has been investigated over a 72-Hour period and based on the 0-Hour measured test concentrations gave the following results:
The EC50 for growth rate was 15 mg/L, with 95 % confdence limits of 13 - 28 mg/L. The NOEC was 7.1 mg/L and the LOEC was 11 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 15 mg/L
Additional information
A study was performed to assess the effect of the test item on the growth of algae according to OECD Guidelines for Testing of Chemicals No 201, using the Growth Inhibition Test.
Preliminary solubility work conducted indicated that it was not possible to obtain a testable solution of the test item using traditional methods of preparation e.g. ultrasonication.
The test item solutions were prepared by stirring an excess of test item in culture medium using a propeller stirrer at approximately 1500 rpm for 24hours. After the stirring period any undissolved test item was removed by filtration.
Analysis of the 18, 32, 56 and 100% v/v saturated solution test preparations at 0 hours showed measured test concentrations to range from 3.65 to 22.2 mg/L. A decline in measured test concentration was observed at 72 hours to between 0.178 and 13.9 mg/L (4.6% to 63% of the 0-Hour measured test concentrations). Analysis of uninoculated aged test preparations at 72 hours gave recoveries of 87 to 103% of the 0-hour measured concentrations, indicating that the test item adsorbed to the algal biomass in the test suspensions. It was therefore considered appropriate to calculate the results based on the 0-Hour measured concentrations only.
The effect of the test item on the growth of Pseudokirchneriella subcapitata has been investigated over a 72-Hour period and based on the 0-Hour measured test concentrations gave the following results:
The EC50 for growth rate was 15 mg/L, with 95 % confdence limits of 13 - 28 mg/L. The NOEC was 7.1 mg/L and the LOEC was 11 mg/L.
All validity criteria were met during the study (cell concentration in control culture increased by a factor of <16 during the exposure; the mean coefficient of variation for section-by-section specific growth in the control was < 35%; the coefficient of variation for average specific growth rate in the control did not exceed 7%).
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