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EC number: 943-502-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: proposed procedure for phytotoxicity testing on Avena sativa and Brassica rapa, 14 d, UBA Berlin, 3/1984
- Principles of method if other than guideline:
- 14-d phytotoxicity test
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Species:
- Brassica rapa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: field mustard
- Plant family: Brassicaceae - Test type:
- seedling emergence and seedling growth test
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 14 d
- Species:
- Brassica rapa
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: seedling emergence and growth
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Principles of method if other than guideline:
- according to Pisker et al. (1984), Seedlings exposed to different test concentrations, root length measurement
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Species:
- other: Lupinus albus
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: White lupine
- Plant family: Fabaceae - Species:
- other: Cicer arietinum
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Chick pea
- Plant family: Fabaceae - Test type:
- other: Root length
- Study type:
- laboratory study
- Substrate type:
- other: test solution
- Limit test:
- no
- Total exposure duration:
- 72 h
- Species:
- other: Lupinus albus
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 384 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: root growth
- Species:
- other: Cicer arietinum
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 361 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: root growth
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Principles of method if other than guideline:
- 11d-toxicity test with concentration series on seedling roots (length of stems, length of longest root, dry weight roots)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Species:
- Hordeum vulgare
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: barley
- Plant family: Poaceae - Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: oat
- Plant family: Poaceae - Test type:
- early seedling growth toxicity test
- Study type:
- laboratory study
- Substrate type:
- other: test solution
- Limit test:
- no
- Total exposure duration:
- 11 d
- Nominal and measured concentrations:
- Nominal: 0, 2, 4, 8, 16, 25, 35, 70, 100 and 200 mg/L (referring to active matter)
- Species:
- Hordeum vulgare
- Duration:
- 11 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: seedling growth
- Species:
- Avena sativa
- Duration:
- 11 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 other: mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: seedling growth
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Qualifier:
- according to guideline
- Guideline:
- other: EEC ring test, C(L1)3: Higher Plant, EEC-Directive 79/831 (1986)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: oat
- Plant family: Poaceae - Species:
- Brassica rapa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Japanese radish
- Plant family: Brassicaceae - Test type:
- early seedling growth toxicity test
- Study type:
- laboratory study
- Substrate type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 21 d
- Species:
- Brassica rapa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 300 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- Brassica rapa
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- Avena sativa
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Qualifier:
- according to guideline
- Guideline:
- other: EEC ring test, C(L1)3: Higher Plant, EEC-Directive 79/831 (1986)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Species:
- Raphanus sativus
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Japanese reddish, leafy daikon
- Plant family: Brassicaceae - Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: oat
- Plant family: Poaceae - Species:
- Lycopersicon esculentum
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: Tomato
- Plant family: Solanaceae - Test type:
- early seedling growth toxicity test
- Study type:
- laboratory study
- Substrate type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 14 d
- Species:
- Raphanus sativus
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 300 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- Raphanus sativus
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Remarks on result:
- other: 10.5% reduced weight at 1000 mg/kg soil
- Species:
- Avena sativa
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- Avena sativa
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Species:
- Lycopersicon esculentum
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 other: mg/kg soil
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Refer to the Category Approach Justification document provided in IUCLID6 Section 13
- Reason / purpose for cross-reference:
- read-across source
- Species:
- Brassica rapa
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: seed emergence and growth
- Remarks on result:
- other: Source, key, 68955-20-4, 1988
Referenceopen allclose all
TGK <= 288 mg/L (toxic threshold concentraion is graphically determined with a mean increase of root length of the controls minus the standard deviation)
The test substance displayed only weak effects on the development of barley and oat seedlings as compared to a control. Effect concentrations are not reported.
Description of key information
Key value for chemical safety assessment
Additional information
In accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related category members was conducted. Read-across data available for C16-18AS Na (CAS 68955-20-4), C12AS Na (CAS 151-21-3) and C12-18AS Na (CAS 68955-19-1) were used.
One reliable study with terrestrial plants is available for C16-18AS Na (CAS 68955-20-4) (Steber 1988). The key non-GLP study followed the procedure for phytotoxicity testing on Avena sativa and Brassica rapa, as described by UBA Berlin (publication series 3/1984) Plants were exposed to the test substance for 14 days in artificial soil. The 14-day EC0 value for Brassica rapa based on seedling emergence and growth was above 1000 mg a.i./kg soil d.w (nominal concentration).
Moreover two additional studies are available (secondary quotation, OECD SIDS 2007). The non-GLP short-term test with Japanese raddish (Raphanus sativus, dicots), oat (Avena sativa, monocots) and tomato plant (Lycopersicon esculentum, dicots) was performed in an EEC ring test, C(L1)3: Higher Plant, EEC-Directive 79/831, 1986 (Henkel, 1995). Early seedling growth toxicity test was carried out for 14 days under laboratory conditions. The lowest NOEC value based on seedling growth was obtained for Raphanus sativus and reached 300 mg/kg soil (nominal concentration). The NOEC values for Avena sativa and Lycopersicon esculentum were above 1000 mg/kg soil (nominal concentrations). The other non-GLP test performed in an EEC ring test, C(L1)3: Higher Plant, EEC-Directive 79/831 (1986), was carried out for 21 days. Japanese radish (Brassica rapa) and oat (Avena sativa) were tested in laboratory conditions in the early seedling growth toxicity test. The NOEC value for Brassica rapa was 300 mg/kg soil d.w. (nominal concentration) and for Avena sativa the NOEC value was 1000 mg/kg soil d.w. (nominal concentration).
One study is available for C12AS Na (CAS 151-21-3; Schmidt 1988). White lupine (Lupinus albus) and chickpea (Cicer arietinum) were tested in a short-term test. Seedlings were exposed to different test concentrations and root length measurement after 72h. The EC50 was 384 mg/L for white lupine and 361 mg/L for chickpea.
Finally, one study is available for C12-18AS Na (CAS 68955-19-1; Hartman 1966). This 11-day toxicity test was performed on seedling roots of barley (Hordeum vulgare) and oat (Avena sativa). Length of stems, length of longest root, dry weight roots were measured. The substance was tested in a nutrient solution containing various concentrations of the test substance up to 200 mg/L. The 11d-EC50 for both species was >200 mg/L based on seedling growth.
The substance is not supposed to be directly applied to soil and further is readily biodegradable. Hence in case of indirect exposure to soil, the substance is expected to rapidly degrade. Therefore soil is not expected to be a compartment of concern.
The Equilibrium Partitioning Method was used to calculate the PNECs values for the terrestrial compartment. The substance exhibits an adsorption coefficient (log Koc) below 5 and is readily biodegradable. In case of exposure to soil, the substance is expected to rapidly degrade, thus the hazard to terrestrial organisms is negligible. Hence, the Equilibrium Partitioning Method is sufficient to calculate the PNECs values for the terrestrial compartment according to the “Guidance on information requirements and chemical safety assessment Chapter R.7c: Endpoint specific guidance”, Section 7.11.6 Integrated Testing Strategy for Effects on Terrestrial Organisms (ECHA 2017).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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