Registration Dossier
Registration Dossier
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EC number: 201-121-3 | CAS number: 78-50-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
A study was conducted to determine the toxicity of the test substance to microorganisms using activated sludge respiration inhibition test according to OECD Guideline 209 and EU Method C.11, in compliance with GLP. The study was conducted under static conditions using freshwater media. Test organisms were exposed to the test substance at loading rates of 0, 10, 100 and 1,000 mg /L. The total exposure period was 3 h and the oxygen consumption was recorded for a period of approximately 10 minutes post exposure. 3,5-dichlorophenol was used as positive control. No inhibition of the respiration rate of the sludge was recorded at any of the loading rates. The EC50of 3,5-dichlorophenol was in the accepted range of 2 to 25 mg/L for total respiration (7.8 mg/L). Under the study conditions, the test substance was not toxic to waste water bacteria (activated sludge) at a loading rate of 1,000 mg/L (NOEL). The EL50was therefore above 1,000 mg/L (Soeter M, 2015).
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