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Diss Factsheets
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EC number: 220-322-7 | CAS number: 2719-27-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance has a low Log Kow measured at 1.79. This low Log Kow (less than 4.5) is an indication that the substance is likely to remain in water indicating not be B or vB. In addition the bioaccumulation factor (predicted from valid EPI suit) is extremely low at 7.12 L/kg. This is well below the > 2000 L/kg threshold which again indicated not B or vB.
With respect to the persistency screening testing indicates that the substance is not readily biodegradable. This is an indication of P or Pv. The predicted (EPI suit) Biowin 3 degradation rate is 2.8 (weeks - months) and is above the 2.2 months probability threshold and is a further indication of P or vP. Other EPI suit predictions also confirm the indication that the substance does not biodegrade readily. The Biowin 5 probability is below 0.5 (estimated probability 0.38) giving an indication that the substance will not biodegrade fast. However other EPI suit predictions (Biowin 1 and 2) show that the substance may biodegrade fast. Based on the EPI suit predictions substance must be considered P but unlikely to be vP.
Cyclohexane carbonyl chloride is not classified as carcinogenic (cat 1A or 1B), cell mutagenic (category 1A or 1B) or toxic for reproduction (category 1A, 1B or 2) in accordance with EC No. 1272/2008. However there are results available from screening tests that shows the EC50 concentrations are well in excess of the <0.1 mg/L criterion to be classed as toxic. Therefore the substance is not T.
The environmental assessment for Cyclohexane carbonyl chloride (CAS 2719-27-9) does not meet the criteria for classification as PTB or vPTB.
- Likely routes of exposure:
Transported isolated intermediates used in stricktly controlled condition.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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