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Diss Factsheets
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EC number: 601-490-4 | CAS number: 117704-25-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From Aug 24 to Sep 25, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch No.: DOA0141202
Purity: 96.6% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): a sewage plan treating predominantly domestic sewage (Nanjing Chengdong Sewage treatment plant).
- Preparation of inoculum for exposure: On the day of test, the test inoculum was prepared by filtering the sample of sewage effluent through a coarse filter, (discarding the first 200 mL) and collecting the remaining filtrates. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: BOD bottles
1) Inoculum control: containing inoculum only (1 mL/L);
2) Test: containing test substance (2 mg/L) and inoculum (1 mL/L);
3) Procedure control: containing reference substance (2 mg/L) and inoculum (1 mL/L);
4) Toxicity control: containing test substance (2 mg/L), reference substance (2 mg/L) and inoculum (1 mL/L).
The BOD bottles were fully filled (30 mL) with the aeratedd test medium using a hose which reached down to the bottom of bottle to achieve adequate mixing. Each bottle was filled to ensure that no air bubbles were enclosed.
Bottle numbers of each group: 4 bottles for toxicity control, 20 bottles for inoculum control, 20 bottles for test group, and 20 bottles for reference control.
- Measuring equipment: BOD bottle, pH meter, Dissolved oxygen meter
SAMPLING
- Sampling frequency:
The concentrations of dissolved oxygen in duplicate vessels of each group were determined after addition of prepared solutions to BOD bottles (0 d). Subsequent determinations of concentration of dissolved oxygen for each group, except toxicity control, were made on 0, 2, 5, 7, 11, 14, 18, 21, 25 and 28 d.
The pH and temperature of contents of each bottle were measured after concentration of dissolved oxygen had been determined.
Determinations of DO, pH and temperature in toxicity control group were made at start and after 14 days. - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 25.5
- Sampling time:
- 28 d
- Details on results:
- Oxygen consumption in inoculated blanks was 1.35 mgO2/L after 14 days of incubation, meeting test criteria of less than 1.5 mg O2/L. Degradation in toxicity control was 34.3% after 14 days, meeting test criteria of no less than 25% in 14 days.
Test result indicated the test substance was not toxic to the inoculum. The lowest level of dissolved oxygen in test substance group was 6.46 mg O2/L, which did not fall below 0.5 mg O2/L and difference of biodegradation of test item in two replicates was less than 20%. - Results with reference substance:
- The biodegradation of reference substance achieved 78% within 14 days, meeting test criteria of achieving 60% within 14 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The biodegradation of test substance was 25.5% after 28 days, means the test substance is not ready biodegradable.
Reference
Description of key information
The biodegradation of test substance was 25.5% after 28 days, means the test substance is not ready biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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