Registration Dossier
Registration Dossier
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EC number: 810-149-0 | CAS number: 1050477-43-4
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- thermal analysis
- Remarks:
- Differential Thermal Analysis (DTA)/Differential Scanning Calorimetry (DSC)
- Melting / freezing pt.:
- >= 220 - <= 260 °C
- Decomposition:
- yes
- Remarks on result:
- other: No pressure is reported
- Between around 220 °C and 260 °C an endothermic effect could be detected. Between approx. 260 °C and 275 °C a second endothermic effect is visible.
- In the range of approx. 280 °C to approx. 335 °C a third endothermic effect could be detected. A decomposition of the test item is indicated by the orange colored residue in the open and the orange-brownish melt in the closed crucible.
- Conclusions:
- CN-ethyl-TH-naphthyridinon has a melting range between 220 °C to 270 °C. No pressure is reported.
- Executive summary:
According to OECD Guidelines for Testing of Chemicals, Section 1 - Physical-Chemical Properties No: 102 "Melting Point / Melting Range" and to Council Regulations EC No 440/2008, Guideline Part A - Methods for the Determination of Physico-Chemical Properties, A.1. "Melting / Freezing Temperature" a melting range between 220 °C to 270 °C could be detected for CN-ethyl-TH-naphthyridinon and no pressure is reported. Between around 220 °C and 260 °C an endothermic effect could be detected. Between approx. 260 °C and 275 °C a second endothermic effect is visible. These two endothermic phases indicate a melting range of the test item. A definite melting point could not be determined.
Reference
Result:
Description of key information
Between around 220 °C and 260 °C an endothermic effect could be detected. Between approx. 260 °C and 275 °C a second endothermic effect is visible. These two endothermic phases indicate a melting range of the test item. A definite melting point could not be determined.
CN-ethyl-TH-naphthyridinon has a melting range between 220 °C to 270 °C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 220 °C
Additional information
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