Registration Dossier
Registration Dossier
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EC number: 287-636-4 | CAS number: 85566-26-3
Endpoint summary
Administrative data
Description of key information
Additional information
The UVCB Fatty acids, C8-10, Me esters (CAS 85566-26-3) is assumed to be not toxic to fish, but toxic to aquatic invertebrates and algae based on a short-term fish study and on results from the main components of the UVCB for aquatic invertebrates and algae. The result of the fish study (Benijts, 1999) determined LC50 (96h) of 100 mg/L indicating the test substance is not toxic to fish. Methyl decanoate (CAS 110-42-9) and methyl octanoate (CAS 111-11-5) were used as read across for Fatty acids, C8-10, Me esters (CAS 85566-26-3) for short-term toxicity to aquatic invertebrates and toxicity to algae, as these both substances are the main components of Fatty acids, C8-10, Me esters. For methyl decanoate (CAS 110-42-9), a SCAE-Me with a C10 chain length, an EC50 of 1.1 mg/L was determined for Daphnia magna. Two QSAR-calculations for methyl octanoate (CAS 111-11-5), with a C8 chain length of the fatty acid, determined an EC50 of 5.6 mg/L (ECOSAR, 2010) and EC50 = 11.6 mg/L (Ohe, 2005) for aquatic invertebrates. The toxicity to algae was evaluated via QSAR-calculation for both main components of Fatty acids, C8-10, Me esters. For methyl decanoate (CAS 110-42-9) the QSAR-calculation yielded an EC50 of 1.35 mg/L (ECOSAR, 2008) and for methyl octanoate (CAS 111-11-5) an EC50 of 4.76 mg/L (ECOSAR, 2008). All QSAR-calculations are assumed to be valid due to good conformities of the EC50-values for structurally related substances in this category with experimental data.
Due to the ready biodegradability of Fatty acids, C8-10, Me esters no toxicity could be expected for microorganisms and the inhibition of the degradation activity of activated sludge is not anticipated.
A long term exposure of the test substance to the aquatic environment is not expected as only low concentrations of the test substance can be expected in the aquatic environment due to the low water solubility and ready biodegradability. In addition, should the substance be taken up, Fatty Acid Methyl Ester will be extensively metabolized by carboxylesterase enzymes.
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