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Diss Factsheets
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EC number: 436-060-3 | CAS number: - FC 84508 PK
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From July 30, 2003 to August 06, 2003
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.5 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 6.3 - <= 7.3
- Conclusions:
- Under the test conditions, the water solubility of the test substance is determined to be <0.5 µg/L at 20 °C
- Executive summary:
A study was performed to determine the water solubility of test substance according to EU Method A.6 and OECD 105 in compliance with GLP.
The test was performed at 20 °C using Column-Elution-Method.
Under the test conditions, the water solubility of the test substance is determined to be <0.5 µg/L at 20 °C
Reference
Description of key information
Three studies according to OECD 105/ECC A.6 have been conducted. The water solubility of the test substance was reported to be <0.5 µg/L, <0.1 mg/L and < 1mg/L at 20 °C. The test substance is considered highly insoluble.
Key value for chemical safety assessment
Additional information
A study was performed to determine the water solubility of test substance according to EU Method A.6 and OECD 105. The test was performed at 20 °C using Column-Elution-Method. The water solubility of the test substance was determined to be <0.5 µg/L at 20 °C. (Schminke A, 2003)
A study was performed to determine the water solubility of test substance according to EU Method A.6 and OECD 105. In the preliminary test, 2 mg of the test substance could not be dissolved in 200 mL of purified water. Therefore the determination of the water solubility of test substance was performed by the column-elution method at 20 °C. Water solubility of the test substance was determined to be <1 mg/L at 20 °C (Schleich W, 2001)
A study was performed to determine the water solubility of test substance according to EU Method A.6 and OECD 105. In the preliminary test, 2 mg of the test substance could not be dissolved in 200 mL of purified water. Therefore, the determination of the water solubility of test substance was performed by the column-elution method at 20 °C. The water solubility of the test substance was determined to be <0.1 mg/L at 20 °C (Schleich W, 2001)
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