Registration Dossier
Registration Dossier
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EC number: 264-150-0 | CAS number: 63449-39-8
Endpoint summary
Administrative data
Description of key information
Additional information
The potential for uptake and accumulation of the substance by fish and other aquatic and terrestrial organisms is uncertain, but appears to decrease with increasing carbon chain length and increasing degree of chlorination. The model estimated BCFs in fish for the LCCP are as follows (method taken from the EU Technical Guidance Document parabolic equation, application for substances with log Kow >6 and molecular weight < 700 g/mol: log BCF = -0.2 x(log Kow)2+ (2.74 x log Kow – 4.72); (Veith et al, 1979):
C18‑20liquid LCCP BCF = 1,096 L/kg
C20-30liquid LCCP BCF = 192 L/kg
C20-30solid LCCP BCF <1 L/kg
There is evidence from feeding studies that LCCPs can be taken up via the diet, but in all cases the concentrations reached in the animals were less than those in the diet. This indicates that although uptake of the substance can occur via the food, the levels should not increase through the food chain (UK EA 2009).
Based on the estimates of BCF and taking the known accumulation properties of structurally similar substances (SCCPs and MCCPs) into account, the BCF for LCCPs is considered to be <2,000 L/kg (UK EA, 2009). Thus it is concluded that LCCPs are unlikely to meet the B or vB (very bioaccumulative) EU criteria.
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