Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
epidemiological data
Type of information:
experimental study
Adequacy of study:
weight of evidence

Data source

Reference
Reference Type:
publication
Title:
Occupational exposure to HI-SIL and SILENE.
Author:
Plunkett ER, DeWitt BJ
Year:
1962
Bibliographic source:
Arch. Environ. Health, 5, 469-472

Materials and methods

Study type:
other: Monitoring at workplace and health check of workers
Endpoint addressed:
repeated dose toxicity: inhalation
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Silicic acid, calcium salt
EC Number:
215-710-8
EC Name:
Silicic acid, calcium salt
Cas Number:
1344-95-2
Molecular formula:
CaSiO3
IUPAC Name:
calcium oxosilanediolate
Details on test material:
Note: The exposure to the target compound overlaps with exposure to a silica that was also produce in that plant:
Hi-Sil (synthetic amorphous silica, precipitated).

- Name of test material (as cited in study report): Silene EF
- Substance type: inorganic
- Physical state: solid; white powder
- Analytical purity:
- Analytical data before ignition: SiO2 (64 %); CaO (18 %); Al2O3 (0.6 %); MgO (0.1 %); NaCl (1.5 %);
- loss at 105 °C: 5 %
- loss on ignition: 15 %
- pH ~10 (5 % water suspension)
- surface area: 80 m2/g

Method

Type of population:
occupational
Ethical approval:
not applicable
Exposure assessment:
measured

Results and discussion

Applicant's summary and conclusion