Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-126-4 | CAS number: 10544-72-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
This information is read across from the Lead Registrants dossier for potassium nitrate (EC # 231-818-8).
The NOEC is 6.75 mmol N/L (i.e. 682 mg KNO3/L or 419 mg nitrate/L)
Key value for chemical safety assessment
Additional information
In water, dinitrogen tetraoxide (EC 234-126-4) will decompose to nitrous acid and nitric acid, and the aquatic toxicity should be equal to the water concentrations of these substances due to the decomposition of the actual concentrations of dinitrogen tetraoxide. (European Commission). Nitrous acid molecules then combine to produce nitric acid, nitric oxide and water.
The overall reaction can be written as follows:
3 N2O4 + 2 H2O = 4 HNO3 + 2 NO
This reaction is known to be rapid (Masteller & Berman), with Larkin having made calculations assuming an instantaneous rate of reaction between dinitrogen tetraoxide and water.
Since nitric oxide is a gas, it is assumed that only nitric acid is relevant for the aquatic toxicity.
It is therefore considered appropriate to read across to nitric acid (EC 231-714-2).
Nitric acid in water immediately dissociates into H+ ions and nitrate ions. The H+ ions will cause a significant pH decrease. As regulatory ecotoxicity studies should be conducted at environmentally relevant pH values (usually pH 6-9), the pH of the nitric acid test solutions should be adjusted. Consequently the pH effect is disregarded and the effects potentially caused by nitrate ions should be examined. Nitrate salts are all well soluble and in water immediately dissociate into nitrate ions and its counterions, similar to nitric acid. The counterions, sodium and potassium, are considered not significant in respect of ecotoxicological properties.
Therefore, this endpoint can be covered by a study conducted with potassium nitrate (Admiraal, 1970), which also dissociates in the environment into its ions. In this study, several marine benthic diatoms were exposed to potassium nitrate. The derived NOEC is 6.75 mmol N/L (i.e. 682 mg KNO3/L or 419 mg nitrate/L). References: 1. European Commission, ESIS (2000) IUCLID Dataset, Dinitrogen tetraoxide (CAS #10544-72-6) p.10 (CD-Rom edition). 2. Masteller, R.D. & Berman, L.D. (1964) Evaluation of the Mechanism of Corrosion in Capillaries, Status report #1, Oxidiser Diffusion Studies DRS S 11047, ME #531. U.S. Department of Defense.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.