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Diss Factsheets
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EC number: 201-853-3 | CAS number: 88-72-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Henry's Law constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- Henry's law constant
- Type of information:
- other: EU Risk Assessment
- Adequacy of study:
- other information
- Reliability:
- other: EU Risk Assessment
- Rationale for reliability incl. deficiencies:
- other: No reliability is given as this is a summary entry for the EU RAR.
- Principles of method if other than guideline:
- EU Risk Assessment
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Analytical purity: not specified
- Executive summary:
EU Risk Assessment (2008):
Several measured values, 5.673 Pa.m3/mol and 5.343 Pa.m3/mol, are mentioned in the SIDS Assessment Report of the OECD, 1994. The experimental dimensionless value given by Altschuh, J. et al. (1999), 5.1·10-4 will be used after conversion to the units needed by means of the equation 22 of the new Technical Guidance Document (TGD), giving a value of 1.2 Pa.m3/mol.
The volatilisation half-life of 2-nitrotoluene from 1 m deep water, flowing 1 m/s with a wind speed of 3 m/s, has been calculated to be 21 hours based on measured Henry's Law constant of 5.6 x10-5atm m3/mol at 25 ºC. A vapour pressure of 0.1 mmHg at 20 ºC for 2-nitrotoluene suggests that this compound will volatilise slowly from dry soil surfaces (OECD, 1994).
- Endpoint:
- Henry's law constant
- Type of information:
- other: BUA report
- Adequacy of study:
- other information
- Reliability:
- other: BUA report
- Rationale for reliability incl. deficiencies:
- other: No reliability is given as this is a summary entry for the BUA report.
- Principles of method if other than guideline:
- BUA report
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Analytical purity: not specified
- H:
- 6.1 Pa m³/mol
- Temp.:
- 20 °C
- Executive summary:
BUA Report, 1989:
The Henry's Law constant of 2-nitrotoluene was reported as 6.1 Pa.m³/mol at 20 °C.
- Endpoint:
- Henry's law constant
- Type of information:
- (Q)SAR
- Adequacy of study:
- other information
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification
- Principles of method if other than guideline:
- Method: other: calculated with HENRYWIN v. 3.10
- GLP compliance:
- no
- Executive summary:
QSAR calculation (Bayer Industry Services, 2006):
The Henry's law constant's value was calculated with the software EPI Suite (HENRYWIN v. 3.10). The QSAR calculation resulted in the following value (bond method): 2.38 Pa*m³/mol at 25°C.
Referenceopen allclose all
EU Risk Assessment (2008):
Several measured values, 5.673 Pa.m3/mol and 5.343 Pa.m3/mol, are mentioned in the SIDS Assessment Report of the OECD, 1994. The experimental dimensionless value given by Altschuh, J. et al. (1999), 5.1·10 -4 will be used after conversion to the units needed by means of the equation 22 of the new Technical Guidance Document (TGD), giving a value of 1.2 Pa.m3/mol.
The volatilisation half-life of 2-nitrotoluene from 1 m deep water, flowing 1 m/s with a wind speed of 3 m/s, has been calculated to be 21 hours based on measured Henry's Law constant of 5.6 x10-5atm m3/mol at 25 ºC. A vapour pressure of 0.1 mmHg at 20 ºC for 2-nitrotoluene suggests that this compound will volatilise slowly from dry soil surfaces (OECD, 1994).
Description of key information
For transported isolated intermediates according to REACh, Article 18, this endpoint is not a data requirement. However, data is available for this endpoint and is thus reported under the guidance of "all available data".
EU Risk Assessment (2008):
Several measured values, 5.673 Pa.m3/mol and 5.343 Pa.m3/mol, are mentioned in the SIDS Assessment Report of the OECD, 1994. The experimental dimensionless value given by Altschuh, J. et al. (1999), 5.1·10-4 will be used after conversion to the units needed by means of the equation 22 of the new Technical Guidance Document (TGD), giving a value of 1.2 Pa.m3/mol.
The volatilisation half-life of 2-nitrotoluene from 1 m deep water, flowing 1 m/s with a wind speed of 3 m/s, has been calculated to be 21 hours based on measured Henry's Law constant of 5.6 x10-5atm m3/mol at 25 ºC. A vapour pressure of 0.1 mmHg at 20 ºC for 2-nitrotoluene suggests that this compound will volatilise slowly from dry soil surfaces (OECD, 1994).
BUA Report, 1989:
The Henry's Law constant of 2-nitrotoluene was reported as 6.1 Pa.m³/mol at 20 °C.
QSAR calculation (Bayer Industry Services, 2006):
The Henry's law constant's value was calculated with the software EPI Suite (HENRYWIN v. 3.10). The QSAR calculation resulted in the following value (bond method): 2.38 Pa*m³/mol at 25°C.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.