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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Toxicity to reproduction

Currently viewing:

Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: read across
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
OECD Toolbox v1.1.02, November 2009

Materials and methods

Test guideline
Guideline:
other: read across
Principles of method if other than guideline:
Estrogen Receptor binding
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzene-1,2,4,5-tetracarboxylic acid
EC Number:
201-879-5
EC Name:
Benzene-1,2,4,5-tetracarboxylic acid
Cas Number:
89-05-4
Molecular formula:
C10H6O8
IUPAC Name:
benzene-1,2,4,5-tetracarboxylic acid

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
other: estrogen receptor binding (%)
Effect level:
0 other: percentage
Based on:
test mat.
Sex:
female
Basis for effect level:
other: The substance shows no Estrogen Receptor Binding

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion