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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Report date:
1953
Reference Type:
study report
Title:
Unnamed
Report date:
1951

Materials and methods

Principles of method if other than guideline:
other: BASF-test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1-vinylimidazole
EC Number:
214-012-0
EC Name:
1-vinylimidazole
Cas Number:
1072-63-5
Molecular formula:
C5H6N2
IUPAC Name:
1-ethenyl-1H-imidazole
Details on test material:
IUCLID4 Test substance: as prescribed by 1.1 - 1.4

Test animals

Species:
mouse

Administration / exposure

Route of administration:
subcutaneous
Vehicle:
water
Doses:
0.25, 0.5, 1.0, 2.0 and 4.0 cm3/kg (ca. 260, 520, 1040, 2080 and 4160 mg/kg bw)
No. of animals per sex per dose:
1 (2080 and 4160 mg/kg bw)
5 (260, 520 and 1040 mg/kg bw)
Control animals:
no

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 750 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion