Registration Dossier
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EC number: 217-915-8 | CAS number: 2008-39-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (21d) = 46.2 mg a.i./L
Key value for chemical safety assessment
Additional information
The chronic effects of dimethylammonium 2,4-dichlorophenoxyacetate (CAS No. 2008-39-1) to aquatic invertebrates were investigated by Mark and Hantink-de Rooy (1989), in a test conducted according to Draft 4, EEC XI 681/86 (1986) and UBA (1984), under GLP conditions. Daphnids (Daphnia magna) were exposed for 21 days to the active substance and effects on survival and reproduction were reported at the highest concentrations tested (100 and 215 mg/L). The resulting NOEC was determined to be 46.2 mg a.i./L.
Dimethylammonium 2,4-dichlorophenoxyacetate is highly soluble and it is rapidly dissociated in water, being 2,4-dichlorophenoxyacetic acid (CAS No. 94-75-7) its main product. This substance was tested in a study by Fochtman (2003) according to OECD Guideline No. 211,Daphnia magnaReproduction test (1998), under GLP conditions. After 21 days of exposure to the test item in a semi-static water regime, a NOEC = 100 mg test substance/L was determined.Ward and Boeri (1991) found similar results when testing 2,4-D acid on Daphnia magna for 21 days under flow-through conditions (EPA/FIFRA Guideline E 72-4), resulting in a NOEC of 79 mg a.i./L.
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