Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-350-0 | CAS number: 82543-18-8
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- other information
- Study period:
- 2001
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Estimation based on chemical structure.
- GLP compliance:
- no
Test material
- Reference substance name:
- 17 alpha-(3-Hydroxypropyl)-6 beta,7 beta;15 beta,16 beta-dimethylene-5 beta-androstane-3 beta,5,17 beta-triol
- EC Number:
- 617-350-0
- Cas Number:
- 82543-18-8
- Molecular formula:
- C24 H38 O4
- IUPAC Name:
- 17 alpha-(3-Hydroxypropyl)-6 beta,7 beta;15 beta,16 beta-dimethylene-5 beta-androstane-3 beta,5,17 beta-triol
- Test material form:
- solid
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- no
Results and discussion
- Transformation products:
- no
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Executive summary:
ZK 92836 does not contain functional groups which are susceptible to hydrolytic cleavage. ZK 92836 is to be considered hydrolytically stable in the relevant pH region 4 - 9.
The test substance molecule and all of its functional groups belong to a class of substances that are generally resistant to hydrolysis, e.g.: alkanes, alkenes, alkynes, benzenes/biphenyls, polycyclic aromatic hydrocarbons, heterocyclic polycyclic aromatic hydrocarbons, halogenated aromatics, aromatic nitro compounds, aromatic amines, alcohols, phenols, glycols, ethers, aldehydes, ketones, carboxylic acids, sulfonic acids (Ref.: Lyman, W. J.; Reehl, W. F.; Rosenblatt, D. H.; Handbook of Chemical Property Estimation Methods, McGraw-Hill New York 1982, p. 7-4).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
